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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 1
2009 3
2013 3
2014 3
2015 1
2016 1
2017 3
2018 5
2019 2
2020 3
2021 3
2022 6
2023 3
2024 0

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35 results

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Page 1
The PI3K Pathway in Human Disease.
Fruman DA, Chiu H, Hopkins BD, Bagrodia S, Cantley LC, Abraham RT. Fruman DA, et al. Among authors: hopkins bd. Cell. 2017 Aug 10;170(4):605-635. doi: 10.1016/j.cell.2017.07.029. Cell. 2017. PMID: 28802037 Free PMC article. Review.
Obesity and Cancer Mechanisms: Cancer Metabolism.
Hopkins BD, Goncalves MD, Cantley LC. Hopkins BD, et al. J Clin Oncol. 2016 Dec 10;34(35):4277-4283. doi: 10.1200/JCO.2016.67.9712. Epub 2016 Nov 7. J Clin Oncol. 2016. PMID: 27903152 Free PMC article. Review.
An atlas of substrate specificities for the human serine/threonine kinome.
Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, van Vlimmeren AE, Andrée-Busch N, Käufer NF, Dorovkov MV, Ryazanov AG, Takagi Y, Kastenhuber ER, Goncalves MD, Hopkins BD, Elemento O, Taatjes DJ, Maucuer A, Yamashita A, Degterev A, Uduman M, Lu J, Landry SD, Zhang B, Cossentino I, Linding R, Blenis J, Hornbeck PV, Turk BE, Yaffe MB, Cantley LC. Johnson JL, et al. Among authors: hopkins bd. Nature. 2023 Jan;613(7945):759-766. doi: 10.1038/s41586-022-05575-3. Epub 2023 Jan 11. Nature. 2023. PMID: 36631611 Free PMC article.
PI3K drives the de novo synthesis of coenzyme A from vitamin B5.
Dibble CC, Barritt SA, Perry GE, Lien EC, Geck RC, DuBois-Coyne SE, Bartee D, Zengeya TT, Cohen EB, Yuan M, Hopkins BD, Meier JL, Clohessy JG, Asara JM, Cantley LC, Toker A. Dibble CC, et al. Among authors: hopkins bd. Nature. 2022 Aug;608(7921):192-198. doi: 10.1038/s41586-022-04984-8. Epub 2022 Jul 27. Nature. 2022. PMID: 35896750 Free PMC article.
Suppression of insulin feedback enhances the efficacy of PI3K inhibitors.
Hopkins BD, Pauli C, Du X, Wang DG, Li X, Wu D, Amadiume SC, Goncalves MD, Hodakoski C, Lundquist MR, Bareja R, Ma Y, Harris EM, Sboner A, Beltran H, Rubin MA, Mukherjee S, Cantley LC. Hopkins BD, et al. Nature. 2018 Aug;560(7719):499-503. doi: 10.1038/s41586-018-0343-4. Epub 2018 Jul 4. Nature. 2018. PMID: 30051890 Free PMC article.
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2.
Bhardwaj P, Iyengar NM, Zahid H, Carter KM, Byun DJ, Choi MH, Sun Q, Savenkov O, Louka C, Liu C, Piloco P, Acosta M, Bareja R, Elemento O, Foronda M, Dow LE, Oshchepkova S, Giri DD, Pollak M, Zhou XK, Hopkins BD, Laughney AM, Frey MK, Ellenson LH, Morrow M, Spector JA, Cantley LC, Brown KA. Bhardwaj P, et al. Among authors: hopkins bd. Sci Transl Med. 2023 Feb 22;15(684):eade1857. doi: 10.1126/scitranslmed.ade1857. Epub 2023 Feb 22. Sci Transl Med. 2023. PMID: 36812344 Free PMC article.
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
Pauli C, Hopkins BD, Prandi D, Shaw R, Fedrizzi T, Sboner A, Sailer V, Augello M, Puca L, Rosati R, McNary TJ, Churakova Y, Cheung C, Triscott J, Pisapia D, Rao R, Mosquera JM, Robinson B, Faltas BM, Emerling BE, Gadi VK, Bernard B, Elemento O, Beltran H, Demichelis F, Kemp CJ, Grandori C, Cantley LC, Rubin MA. Pauli C, et al. Among authors: hopkins bd. Cancer Discov. 2017 May;7(5):462-477. doi: 10.1158/2159-8290.CD-16-1154. Epub 2017 Mar 22. Cancer Discov. 2017. PMID: 28331002 Free PMC article.
Cancer metabolism gets physical.
DelNero P, Hopkins BD, Cantley LC, Fischbach C. DelNero P, et al. Among authors: hopkins bd. Sci Transl Med. 2018 May 23;10(442):eaaq1011. doi: 10.1126/scitranslmed.aaq1011. Sci Transl Med. 2018. PMID: 29794058 Free PMC article. Review.
Epinephrine inhibits PI3Kα via the Hippo kinases.
Lin TY, Ramsamooj S, Perrier T, Liberatore K, Lantier L, Vasan N, Karukurichi K, Hwang SK, Kesicki EA, Kastenhuber ER, Wiederhold T, Yaron TM, Huntsman EM, Zhu M, Ma Y, Paddock MN, Zhang G, Hopkins BD, McGuinness O, Schwartz RE, Ersoy BA, Cantley LC, Johnson JL, Goncalves MD. Lin TY, et al. Among authors: hopkins bd. Cell Rep. 2023 Dec 26;42(12):113535. doi: 10.1016/j.celrep.2023.113535. Epub 2023 Dec 4. Cell Rep. 2023. PMID: 38060450 Free PMC article.
Phosphatidylinositol 3-Kinase, Growth Disorders, and Cancer.
Goncalves MD, Hopkins BD, Cantley LC. Goncalves MD, et al. Among authors: hopkins bd. N Engl J Med. 2018 Nov 22;379(21):2052-2062. doi: 10.1056/NEJMra1704560. N Engl J Med. 2018. PMID: 30462943 Review. No abstract available.
35 results